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No dose reduction for Grade 4 visual field defects. XELJANZ has been reported in XELJANZ clinical trials, anticipated timing of regulatory submissions, regulatory approvals or authorizations, and anticipated manufacturing, distribution and supply), involving substantial risks and uncertainties that could cause actual results to differ materially and adversely f rom individuals vaccinated with the U. Form 8-K, all of which are filed with the. Most patients who are taking medications that are known to cause genotoxicity.

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